Process for the preparation of pyridine dicarboxylate derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546319, C07D21330

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active

058920501

ABSTRACT:
There is provided a single vessel process for the preparation of a pyridine dicarboxylate compound of formula I ##STR1## via the sequential condensation of an alkyl vinyl ether with Vilsmeier reagent, oxalacetate and an ammonia source.

REFERENCES:
patent: 4656283 (1987-04-01), Doehner
patent: 4758667 (1988-07-01), Szczepanski et al.
patent: 4997947 (1991-03-01), Szczepanski et al.
patent: 5252538 (1993-10-01), Cross et al.
R.A. Abramovitch, Pyridine and its Derivatives Supplement Part Three, John Wiley & Sons, pp. 268-330 (1974).

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