Process for the preparation of pyrethroid acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562500, 568348, 568364, 568381, C07C 5100

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active

046910522

ABSTRACT:
Pyrethroid acids are prepared by conducting a cycloaddition reaction of a conjugated diene and a dihaloketene to form a dihalo-vinylcyclobutanone product; reducing the dihalo-vinylcyclobutanone product to a monohalo-vinylcyclobutanone product and then conducting a ring contraction with a base to form the desired acid product.

REFERENCES:
patent: 4028418 (1977-06-01), Brink
patent: 4064174 (1977-12-01), Verbrugge
patent: 4242278 (1980-12-01), Martin
patent: 4284821 (1981-08-01), Martin
patent: 4291176 (1981-09-01), Heine
patent: 4390719 (1983-06-01), Schwarze
Krepski, J. Org. Chem., 43, pp. 2879-2882 (1978).
Bak, J. Org. Chem, 44, pp. 107-110 (1979).
Elliott, Chem. Soc. Rev., 7, pp. 473-475 (1978).

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