Process for the preparation of purified vancomycin class antibio

Details Process for the preparation of purified vancomycin class antibio Process for the preparation of purified vancomycin class antibio

1983-07-13

1987-05-19

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 185, 536127, 530412, 530417, C07H 100, C07C10352

Patent

active

046670246

ABSTRACT:
A novel process for the isolation and purification of vancomycin class antibiotics which utilized affinity chromatography by the formation of a sorption complex between the antibiotic and an immobilizing ligand selected from -D-alanyl-D-alanine or -X-D-alanyl-D-alanine, wherein X is an amino acid radical and the novel affinity chromatography sorbent employed therein are disclosed.

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Williams et al., "Topics in Antibiotic Chemistry", 5, pp. 119-158; 1980.
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