Process for the preparation of purified bacterial membranal prot

Details Process for the preparation of purified bacterial membranal prot Process for the preparation of purified bacterial membranal prot

1979-12-13

1981-10-27

Brown, Johnnie R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

420 92, 420177, C07G 700, A61K 39108, A61K 3902

Patent

active

042972728

ABSTRACT:
This invention relates to a process for the preparation of purified bacterial membranal proteoglycans. The process comprises at least one step in which crude proteoglycans are treated in aqueous medium with a base or a hypobromite, followed by elimination of the excess reactant and the insoluble residue, the purified proteoglycans being present in aqueous solution. The thus obtained purified proteoglycans may be used as immunity adjuvants in vaccines without causing side-effects such as pyrogenic reactions.

REFERENCES:
patent: 3408440 (1968-10-01), Voss
patent: 3956481 (1976-05-01), Jolles et al.
patent: 4001395 (1977-01-01), Jolles et al.
patent: 4108849 (1978-08-01), Thomas

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