Process for the preparation of purified aminoglycoside antibioti

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 136, 536 168, 536 169, C07H 1522

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043806252

ABSTRACT:
The invention relates to an improved process for the isolation and purification of aminoglycoside antibiotics of Formula (I) as defined herein combining selective lipophilization of the compound of Formula (I) in the crude product obtained by fermentation with controlled liquid/liquid extraction.

REFERENCES:
patent: 4107435 (1978-08-01), Ross
patent: 4180565 (1979-12-01), Mallams et al.
patent: 4190722 (1980-02-01), Voss et al.
patent: 4224315 (1980-09-01), Stadler et al.

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