Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2005-02-22
2005-02-22
Raymond, Richard L. (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C544S261000
Reexamination Certificate
active
06858731
ABSTRACT:
A process for preparing and concentrating (6S,αS) or (6S,αR) tetrahydrofolic acid ester salts and (6S,αS) or (6S,αR) tetrahydrofolic acid, characterized by preparing or dissolving equimolar or concentrated mixtures of diastereomers of addition salts of tetrahydrofolic acid esters with aromatic sulphonic acids in organic solvents, followed by crystallizing them at least once, and then if applicable hydrolyzing the crystallizate to produce (6S,αS) or (6S,αR) tetrahydrofolic acid, crystallizing the latter as a free acid or isolating it in the form of a salt.
REFERENCES:
patent: 5006655 (1991-04-01), Müller et al.
patent: 5300503 (1994-04-01), Peake et al.
patent: 5324836 (1994-06-01), Muller et al.
patent: 5489684 (1996-02-01), Jequier et al.
patent: 5698693 (1997-12-01), Fitzhugh et al.
patent: 6271374 (2001-08-01), Müller et al.
patent: 6596721 (2003-07-01), Müller et al.
patent: 20010002398 (2001-05-01), Müller et al.
patent: 0 348 641 (1990-01-01), None
patent: 0348641 (1990-01-01), None
patent: 0 495 204 (1992-07-01), None
patent: 0495204 (1992-07-01), None
patent: 0 537 492 (1993-04-01), None
patent: 0537492 (1993-04-01), None
patent: 0 682 026 (1995-11-01), None
patent: 0682026 (1995-11-01), None
Groehn Viola
Moser Rudolf
Muller Hans Rudolf
EPROVA AG
Millen White Zelano & Branigan P.C.
Raymond Richard L.
Truong Tamthom N.
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