Process for the preparation of pure 3-acetylamino-anilines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564218, C07C10200, C07C10204

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045408157

ABSTRACT:
Process for the preparation of pure 3-acetylaminoanilines of the general formula (1) ##STR1## in which R denotes a hydrogen atom or an alkoxy group with 1-4 carbon atoms, by reduction of 1,3-dinitrobenzene in an alkanol with 1-4 carbon atoms to the 1,3-diaminobenzene or by reaction of 2,4-dinitrochlorobenzene with sodium hydroxide in an alkanol with 1-4 carbon atoms and subsequent reduction to the 2,4-diaminoalkoxybenzene, and in each case subsequent monoacetylation in the alkanol mentioned to give the 1-amino-3-acetylamino-benzene or the 2-amino-4-acetylamino-alkoxy-benzene and isolation of the compound of the above formula (1) obtained in the alkanolic solution, which optionally contains water, which comprises carrying out the isolation by precipitation of the compound of the above formula (1), in the form of the hydrohalide, from the alkanolic solution by means of hydrogen halide or aqueous hydrogen halide acid and subsequent filtration.

REFERENCES:
patent: 3857886 (1974-12-01), Hewsel et al.
patent: 3919269 (1975-11-01), Jaffe et al.
patent: 3960886 (1976-06-01), Schulenberg

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