Process for the preparation of pteridine derivatives

Details Process for the preparation of pteridine derivatives Process for the preparation of pteridine derivatives

1986-11-17

1988-08-30

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544260, 556410, 556412, A61K 31495, C07D47504, C07D47508

Patent

active

047678593

ABSTRACT:
Pteridine derivatives of general formula ##STR1## in which R is hydrogen or methyl, i.e. aminopterin or methotrexate, are made by the action of a silazane on a pteridine derivative of formula ##STR2##

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