Process for the preparation of prostaglandin analogues and...

Details Process for the preparation of prostaglandin analogues and... Process for the preparation of prostaglandin analogues and...

2011-03-01

2011-03-01

Chandrakumar, Nizal S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C560S055000, C560S121000

Reexamination Certificate

active

07897795

ABSTRACT:
The present application provides intermediates for preparing prostaglandin analogues and processes for preparing prostaglandin analogues and intermediates thereof. The intermediates include: A compound of formula (6):R1represents H, C1-C5-alkyl, or benzyl, in particular isopropyl.

REFERENCES:
patent: 5106750 (1992-04-01), Wong et al.
patent: 5191109 (1993-03-01), Minai et al.
patent: 5618959 (1997-04-01), Trampota et al.
patent: 6214611 (2001-04-01), Fox et al.
patent: 6313341 (2001-11-01), Murata et al.
patent: 6852880 (2005-02-01), Ham et al.
patent: 7109371 (2006-09-01), Clissold et al.
patent: 1384024 (1975-02-01), None
patent: 56-46833 (1981-04-01), None
patent: 63-77837 (1988-04-01), None
patent: 3077878 (1991-04-01), None
patent: 5213924 (1993-08-01), None
patent: WO95/33845 (1995-12-01), None
Linderman et al., Synthesis of and Analysis of Thiol Additions to β-Alkylα-a, β-unsaturated Trifluoromethyl Ketones,J. Org. Chem. 1994,59, 957-962.
Renaldo et al., Palladium-Catalyzed Coupling of Acid Chlorides with Organotin Reagents: Ethyl (E)-4-(4-Nitrophenyl)-4-oxo-2-butenoate[2-Butenoic acid, 4-(4-nitrophenyl)-4-oxo-, ethyl ester, (E)-],Organic Syntheses, Coll. vol. 8, p. 268 (1993); vol. 67, p. 86 (1989).
Marshall et al., Generation of Noracemic 2-(t-Butyldimethylsilyloxy)-3-Butynylithium From (S)-Ethyl Lactate:[(S)-4-(t-Butyldimethylsilyloxy)-2-Pentyn-1-Ol],Organic Syntheses, vol. 81, p. 157 (2005).
Rodri´guez et al., An Efficient Asymmetric Synthesis of Prostaglandin E1,Eur. J. Org. Chem. 1999, 2655-2662.
Hodgson et al., A Two-directional Synthesis of the C58-C71 fragament of Palytoxin,Org. Biomol. Chem., 2004, 2, 373-386.
Fox et al., An Entantiocovergent Syntheis of (R)-4-Aryloxy-1-butyne-3-ols for prostanoid Side Chains,Adv. Synth. Catal. 2002, 344, No. 1, 50-56.
Floyd, Prostagalandins and Congeners. 18. Synthesis of Cyclopentenolon Precursors to Prostaglandsins from 2,5-Dihydro-2,5-dimethoxyfurans,J. Org. Chem. vol. 43, No. 9, 1978, 1641-1643.

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