Process for the preparation of polyhalogenated benzotrifluorides

Details Process for the preparation of polyhalogenated benzotrifluorides Process for the preparation of polyhalogenated benzotrifluorides

1996-06-26

2000-06-13

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic halides

562860, C07L 5158

Patent

active

060751657

ABSTRACT:
Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogeno-benzotrichlorides and -benzoyl chlorides
Polyhalogenated benzotrifluorides can be reacted with chlorides from the series of Friedel-Crafts catalysts to give the corresponding benzotrichlorides, which can be hydrolysed by water in the presence of iron(III) chloride to give the corresponding benzoyl chlorides. These are suitable as intermediate products for the preparation of active compounds for medicaments and feed additives.

REFERENCES:
patent: 1557154 (1925-10-01), George
patent: 1880169 (1932-09-01), Bennett et al.
patent: 3411886 (1968-11-01), Burk
patent: 4276231 (1981-06-01), Bockmann et al.
patent: 4582948 (1986-04-01), Tang et al.
patent: 4588726 (1986-05-01), Petersen et al.
patent: 4704483 (1987-11-01), Tang et al.
patent: 4769492 (1988-09-01), Kaieda et al.
patent: 4978769 (1990-12-01), Kysela et al.
patent: 5072038 (1991-12-01), Klauke et al.
patent: 5075319 (1991-12-01), Lesher et al.
patent: 5169853 (1992-12-01), Lesher et al.
patent: 5200548 (1993-04-01), Klauke et al.
patent: 5599980 (1997-02-01), Marhold et al.
K.V. Dvornikova, et al., Preparation of Polyfluorobenzotrihalides by the Reactions of Octafluorotoluene and its Derivatives With Aluminum Halides. Synthesis of Polyfluorostilbenes and Decafluorotolan, Plenum Publishing Corporation, pp. 525-532, (1991).
L. Andersen, et al., J. Chem. Soc. C., (1969), (2), 211-17.
Y. Pozdnyakovich, et al., J. Fluorine Chem., (1974), 4, (3), 283-96.
J. Bailey, et al., J. Fluorine Chem., (1987), 37, (1), 1-14.
Derwent Abstract of JP 61155350 (Jul. 15, 1986).
Derwent Abstract of JP 62289534 (Dec. 16, 1987).
L.P. Anderson, et al. Diels-Alder Reactions of Polyfluorocyclohexa-1,3-dienes. Part I. Addition of Alkynes to Perfluorocyclohexa-1,3-diene. A Route to ortho-Disubstituted Tetrafluorobenzenes J. Chem. Soc. C., (1969) pp. 211-217.
Bailey et al. Fluorinations with Complex Metal Fluorides. Part 9. Fluorinations of Toluene and Xylene Derivatives by Means of Caesium Tetrafluorocobaltate[III] Journal of Fluorine Chemistry, vol. 37, (1987) pp. 1-14.
Pozdnyakovich et al. Fluorine-containing Carbocations II. Polyfluorinated Benzyl Cations Journal of Fluorine Chemistry, vol. 4 (1974) pp. 283-286.
Derwent Abstract: Pharmaceuticals, p. 18, Week 9028, ASAG, B02, 90-214423/JO 2145-538-A; "Pharmaceuticals Intermediate Fluoro-benzoic Acids . . . ", Asahi Glass KK.
Derwent Abstract: General Chemistry, Week 8910, NICA, E14, 89-073118/10, JO 1025-737-A; "Prepn. of Halogenzene(s) and /or Halo-benzoic Acid(s) . . . ", Nippon Carbide Kogy KK.
Derwent Abstract: Pharmaceuticals, p. 6, Week 8903, MITN, B05, 89-019649/03, J6 3295-529-A; "Prepn. of 2,3,4,5-Tetra:fluoro:benzoic Acid . . . ", Mitsubishi Gas Chem. KK.
Derwent Abstract: Pharmaceuticals, p. 5, Week 8717, WARN, B05, 87-102612/15, J6 2061-948-A; "Improved Route to 2,3,4,5-tetra: fluoro-benzoic acid . . . ", Warner-Lambert.
Chemical Abstracts of Japan, vol. 13, Abstract No. C07C63/70.
Chemical Abstracts, Abstract of De 2,344,603, Abstract No. 8638u (1974).
Japanese Patent Laid-Open Application (KOKAI) No. 1-13037-A (Ihara Chemical Ind. Co., Ltd.), Jan. 17, 1989.

Affiliated with

Also associated with

Rating

Process for the preparation of polyhalogenated benzotrifluorides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of polyhalogenated benzotrifluorides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of polyhalogenated benzotrifluorides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2069946