Process for the preparation of phosphorus derivatives of seconda

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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544 17, C07D49914, C07D50104

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040827453

ABSTRACT:
An improvement in the conversion of penam and cephem compounds to secondary ammonium salts of phosphite amides thereof by reacting as follows: ##STR1## wherein --R, is the non-reacting balance of the penam or cephem compound and ##STR2## ARE NON-REACTING SUBSTITUENTS. Catalytic amounts of H--N< or the hydrogenhalide thereof may be present in the reaction medium.

REFERENCES:
patent: 3926954 (1973-12-01), Kiesewetter et al.
patent: 3932391 (1976-01-01), Alburn et al.
patent: 3953436 (1976-04-01), Spry
patent: 3962215 (1976-06-01), Sellstedt
patent: 3994883 (1976-11-01), Borrevang et al.
patent: 3994911 (1976-11-01), Sellstedt

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