Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1994-07-07
1995-08-15
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
558124, 560 30, 560 38, 560150, 560161, 560172, 562555, 562574, C07C27122, C07C31119, C07C22718, C07F 940
Patent
active
054420881
ABSTRACT:
Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process
L-amino acids of the formula I and salts thereof, ##STR1## in which R.sup.1 to R.sup.5 are defined as in claim 1 and n is 0 or 1, are obtained according to the invention by
a) reacting an optically active S-homoserine lactone of the formula II, ##STR2## with hydrogen chloride in the presence of an alcohol of the formula R.sup.5 --OH to give novel compounds of the formula III, ##STR3## in which R.sup.3, R.sup.4 and R.sup.5 are defined as in formula I, except that R.sup.5 =H, and
b) reacting the resulting compound of formula III with a compound of formula IV,
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Ambrose M.
Hoechst Aktiengesellschaft
Lee Mary C.
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