Process for the preparation of perindopril

Details Process for the preparation of perindopril Process for the preparation of perindopril

2007-11-06

2007-11-06

McKane, Joseph K. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

11386011

ABSTRACT:
A process for preparing perindopril is provided comprising condensing an N-[(S)-1-carbethoxybutyl]-(S)-alanyl halide of formula II:wherein X is a halide with an (2S,3aS,7aS)-2-carboxyperhydroindole of formula III:wherein R is hydrogen or a protecting group.

REFERENCES:
patent: 4914214 (1990-04-01), Vincent et al.
patent: 1 279 665 (2003-01-01), None
patent: 1 367 061 (2003-12-01), None
patent: 2 004 804 (1989-02-01), None
patent: WO 96/33984 (1996-10-01), None
patent: WO 200158868 (2001-08-01), None
patent: WO 2004/075889 (2004-09-01), None
patent: WO 2005/105762 (2005-11-01), None
patent: WO 2005/113500 (2005-12-01), None
Ogata Masaru et al., “N-(Chlorosulfinyl)-imidazole as a new imidazole transfer reagent” Synthetic Communications, 10(10), pp. 733-742 (1980).
Coll, Alberto Palomo, “Formation of new N-sulfoxyanhydrides as intermediates for the synthesis of ACE inhibitors” Afinidad 57(487), pp. 209-210(2000).

Affiliated with

Also associated with

Rating

Process for the preparation of perindopril does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of perindopril, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of perindopril will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3859214