Process for the preparation of pantoprazole and salts thereof

Details Process for the preparation of pantoprazole and salts thereof Process for the preparation of pantoprazole and salts thereof

2006-07-25

2006-07-25

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07081534

ABSTRACT:
A process for the preparation of pantoprazole and the salts thereof, comprising the reaction of a mercaptoimidazole with a picoline, to give a 2-pyridinyl-methylsulfinyl-2-benzimidazole intermediate, the oxidation thereof with ε-phthalimidoperhexanoic acid and the subsequent methoxylation.

REFERENCES:
patent: 6124464 (2000-09-01), Hogberg et al.
patent: 6723852 (2004-04-01), Berenguer Maimo
patent: 1 466 897 (2004-10-01), None
patent: WO 02/28852 (2002-04-01), None
Modi et al., “A process for the manufacture, etc.,” CA 140: 270848 (1997).
Mathad et al., “An Improved and single, etc.”, Organic Process Research & Development, 2004, 8, 266-270.

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