Process for the preparation of optically active anthracycline gl

Details Process for the preparation of optically active anthracycline gl Process for the preparation of optically active anthracycline gl

1981-12-28

1983-09-20

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435886, C12P 1956, C12R 1465

Patent

active

044057130

ABSTRACT:
There is presented the compounds 4-deoxy-aclacinomycin A and B and pharmaceutical preparations containing the same. The preparations are effective against bacteria and tumours. Also presented is a process for the preparation of optically active anthracycline glycosides A and B with the 7S-configuration starting from racemic anthracyclinones.

REFERENCES:
patent: 3988315 (1976-10-01), Umezawa et al.
patent: 4329339 (1982-05-01), Fujiwara et al.
patent: 4375511 (1983-03-01), Fujiwara et al.
Blumauerova et al., Genetics of Industrial Microorganisms, Proceedings of the Third Int. Sym. on Genetics of Ind. Microorg., Am. Soc. for Microbiol., Washington, D.C., 90-96 (1979).
Oki et al., J. Antibiotics, 33(11): 1331-1340 (1980).
Oki et al., J. Antibiotics, 28(10), 830-834 (1975).

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