Process for the preparation of optically active acyloxyazetidino

Details Process for the preparation of optically active acyloxyazetidino Process for the preparation of optically active acyloxyazetidino

1992-10-22

1994-05-31

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540200, 549548, 435121, C07D20508, C07D30348, C07B 4112

Patent

active

053171004

ABSTRACT:
Compounds of the formula ##STR1## in which R.sub.1 is hydrogen or lower alkyl, R.sub.2 is hydrogen or a hydroxyl protective group R.sub.2 ' and R.sub.3 is substituted or unsubstituted phenyl or lower alkyl can be prepared in a three-stage process from readily accessible .beta.-lactam starting materials.

REFERENCES:
patent: 3452000 (1969-06-01), Testa et al.
patent: 4260627 (1981-04-01), Christensen
patent: 4871841 (1989-10-01), Ermann
patent: 4882429 (1989-11-01), McCombie
Hanessian, J. Am. Chem. Soc. 107, 1438 (1985).
Sohar, Appl. Microbiol. Biotechnol. 27, 451-456 (1988).
Webber, Chem. Abst. 76, 140851x (1972).
Johnson, Chem. Abstr. 90, 103514h (1978).
Sumitomo, Chem. Abstr. 94, 139373s (1980).
Inst. Physical and Chem. Res., Chem. Abst. 94, 192502a (1980).
Komendantov, Chem. Abstr. 104, 224577 (1985).
Terajima, Chem. Abst. 108, 131830s (1987).
Geiger "The Peptides" (Academic Press, Inc. 1981) vol. 3, pp. 6-7.
McCombie "Protective Groups in Organic Synthesis", (1973) p. 48.
Gould, "Mechanism & Structure in Organic Chemistry", pp. 317-318 (1959).
March, Adv. Org. Chemistry 3rd Ed. (1985) p. 298.
Chem Abstr. 89, 1978, 197031c, Momose.
House, "Modern Synthetic Reactions", 2nd Ed. pp. 321-328, 1972.
Yao, Analytica Chemica Acta 207, 319-323 (1988).
Sankyo Chem. Abstr. 103, 123272t, 1985.
Derwent Abstr. for EP 181,831, published 1986.

Affiliated with

Also associated with

Rating

Process for the preparation of optically active acyloxyazetidino does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of optically active acyloxyazetidino, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of optically active acyloxyazetidino will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1628862