Process for the preparation of optically active 2-methyl-1,2-hex

Details Process for the preparation of optically active 2-methyl-1,2-hex Process for the preparation of optically active 2-methyl-1,2-hex

1989-04-26

1990-05-01

Evans, J. E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568868, 568872, C07C 29136, C07C 3120

Patent

active

049220322

ABSTRACT:
Disclosed is the preparation of both optically active stereoisomers of 2-methyl-1,2-hexanediol, which are useful intermediates for the syntheses of several prostaglandins for peptic ulcer therapy.

REFERENCES:
patent: 4633025 (1985-12-01), Corey
patent: 4668822 (1987-05-01), Corey
Lynch et al., (1984) J. Amer. Chem. Soc. 106: 2943-48.
Eliel et al. (1987) Org. Synth. 65: 215-222.
Collins (1986) J. Med. Chem. 29: 437-443.

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