Process for the preparation of optically active 2-arylalkanoic a

Details Process for the preparation of optically active 2-arylalkanoic a Process for the preparation of optically active 2-arylalkanoic a

1989-01-27

1991-07-23

Rosen, Sam

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435141, C12P 752

Patent

active

050343297

ABSTRACT:
Optically active 2-arylalkanoic acids are made by enantioselective hydrolysis of the corresponding racemic amides in the presence of a microorganism, or of an enzyme derived therefrom, able selectively to hydrolyse racemic .alpha.-phenylpropionamide to S .alpha.-phenylpropionic acid.

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Chemical Abstracts, vol. 91, 1979, p. 610.
Chemical Abstracts, vol. 83, 1975, pp. 471-472 (27810).
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Zbl. Bakt. Hyg., I. Abt. Orig. A220, 452-456 (1972) Frommer et al.
Thiery et al., Chem. Abst. vol. 105 (1986), p. 167,595w.
Dotani et al., Chem. Abst. vol. 104 (1986), p. 166,912q.

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