Process for the preparation of olmesartan medoxomil

Details Process for the preparation of olmesartan medoxomil Process for the preparation of olmesartan medoxomil

2011-05-17

2011-05-17

Chung, Susannah (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S253000

Reexamination Certificate

active

07943779

ABSTRACT:
The present invention relates to an improved process for the manufacture of olmesartan and pharmaceutically acceptable salts and esters thereof as an active ingredient of a medicament for the treatment of hypertension and related diseases and conditions.

REFERENCES:
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Koike et al. 2003 Annual Report of Sankyo Research Laboratories 55:1-89.
Yanagisawa et al. 1996 “Nonpeptide Angiotensin II Receptor Antagonists: Synthesis, Biological Activities, and Structure-Activity Relationships of Imidazole-5-carboxylic Acids Bearing Alkyl, Alkenyl, and Hydroxyalkyl Substituents at the 4-Position and Their Related Compounds”Journal of Medicinal Chemistry39(1):323-338.

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