Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-04-01
1990-11-06
Gerstl, Robert
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549495, C07D27728, C07D30752
Patent
active
049688081
ABSTRACT:
A new process for the preparation of the nitroethane derivatives, ranitidine and nizatidine, is described which takes place via intermediate products and enables the said compounds to be prepared with a higher degree of purity. Another advantage is that in contrast to the known processes, it is not accompanied by the liberation of the highly toxic and malodorous compound, methylmercaptan.
REFERENCES:
patent: 4233302 (1980-11-01), Smith
patent: 4760075 (1988-07-01), Pioch
patent: 4777260 (1988-10-01), Ryan
Rudchenko, Zh Org. Khim. 13, 1383 (1977) Abstract.
Buevich, Zh Org. Khim, 13, 2618 (1977) Abstract.
Ahrens Kurt H.
Mosdorf Peter
Schickaneder Helmut
Gerstl Robert
Heumann Pharma GmbH & Co.
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