Process for the preparation of N,N'-bis-(2-hydroxy-ethyl) pipera

Details Process for the preparation of N,N'-bis-(2-hydroxy-ethyl) pipera Process for the preparation of N,N'-bis-(2-hydroxy-ethyl) pipera

1989-04-21

1990-07-31

Shen, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D29508

Patent

active

049451618

ABSTRACT:
A new process for preparing N,N'-bis-(2-hydroxyethyl)-piperazine (I) ##STR1## is described which involves reaction of oxamide with excess diethanolamine at a temperature of from 50.degree. to 268.degree. C.

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Chenevert et al., Chem. Abst. 100-6485s (1984).
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Enichem Anic S.p.A., Chem. Abst. 109-92287u (1988), JP-621249,958 (eq. EP 245631 cited on Spec. p. 6).
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