Process for the preparation of N-acyl-.alpha.-amino acid derivat

Details Process for the preparation of N-acyl-.alpha.-amino acid derivat Process for the preparation of N-acyl-.alpha.-amino acid derivat

1995-05-02

1997-07-22

Nazario-Gonzalez, Porfirio

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562518, 562517, 562406, C07C 5112

Patent

active

056505370

ABSTRACT:
A process for the preparation of N-acylglycine derivatives of the formula (I) ##STR1## which comprises reacting a carboxylic acid amide with an aldehyde in the presence of a solvent and an acid to give an acylaminomethylol and then carbonylating the acylaminomethylol in the presence of a cobalt carbonyl catalyst.

REFERENCES:
patent: 4891442 (1990-01-01), Lin et al.
patent: 4918222 (1990-04-01), Lin et al.
European Patent Search Report 95106329.6, Jun. 21, 1995.
C. Ferri, "Reaktionen der Organischen Synthese", 1978, Georg Thieme Verlag, Seite 293.

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