Process for the preparation of microcapsules

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424408, 424410, A61K 914

Patent

active

058372903

ABSTRACT:
The invention relates to a process for the preparation of an aqueous suspension of microcapsules having a capsule wall of polyurea and encapsulating a water-immiscible pesticide, by dispersing a solution of a polyisocyanate in the sparingly water-soluble pesticide in water and subsequently reacting the dispersion with a polyamine, which process comprises effecting the dispersion of the solution of the polyisocyanate in the sparingly water-soluble pesticide in water and the subsequent reaction of the dispersion with the polyamine in the presence of at least one water-soluble or water-dispersible nonionic surfactant of a block copolymer having at least one hydrophobic block and at least one hydrophilic block.

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patent: 4230809 (1980-10-01), Heinrich et al.
patent: 4235872 (1980-11-01), Tocker
patent: 4280833 (1981-07-01), Beestman et al.
patent: 4643764 (1987-02-01), Scher
patent: 4851227 (1989-07-01), Markus et al.
patent: 4936901 (1990-06-01), Surgant
patent: 4938797 (1990-07-01), Hasslin et al.
patent: 5354742 (1994-10-01), Deming et al.

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