Process for the preparation of long-chain dicarboxylic acids by

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435176, 435924, C12P 744

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active

043395368

ABSTRACT:
Disclosed in this invention is a process for producing a long-chain dicarboxylic acid by culturing a fungus belonging to Candida tropicalis which has the ability to produce a long-chain dicarboxylic acid in a liquid medium containing a straight-chain saturated hydrocarbon as substrate, the production of said dicarboxylic acid being phenomenally increased by properly adjusting the pH of the medium in the course of culture. There is also disclosed a method for advantageously separating and collecting said dicarboxylic acid from a fermentation broth containing said dicarboxylic acid produced by said culture.

REFERENCES:
patent: 3843466 (1974-10-01), Akabori et al.
patent: 3878093 (1975-04-01), Kanani et al.
patent: 4081367 (1978-03-01), Hulls et al.
patent: 4248971 (1981-02-01), Yousset
Kirk-Othmer Encyclopedia of Chemical Technology, Third Ed., v. 7, pp. 611, 612, Wiley, N.Y., 1978.

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