Process for the preparation of L-phosphinothricin using transami

Details Process for the preparation of L-phosphinothricin using transami Process for the preparation of L-phosphinothricin using transami

1994-07-08

1996-12-24

Marx, Irene

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435106, C12P 4100, C12P 1902

Patent

active

055873197

ABSTRACT:
L-2-Amino-4-methylphosphinobutyric acid can be prepared by a racemate resolution in the presence of D-aminoacid and L-aminoacid transaminases by reaction with .alpha.-keto acids and amino-group donors. In particular, transaminases from Bacillus licheniformis and from Escherichia coli are used.

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Dixon and Webb, Enzymes pp. 75-80 (1964).
Chemical Abstract, vol. 69, No. 58390t (1968).

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