Process for the preparation of l-dopa

Details Process for the preparation of l-dopa Process for the preparation of l-dopa

1969-12-11

1976-07-13

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260519, 2605705CA, 424309, C07C 6350

Patent

active

039693970

ABSTRACT:
The present invention is directed to preparing L-Dopa, an agent effective in the treatment of Parkinson's Disease, from a D,L-N-benzoyl-3-(4-hydroxy-3-methoxyphenyl) alanine utilizing dehydroabietylamine as a resolving agent and intermediates in this process.

REFERENCES:
patent: 3347928 (1967-10-01), Taub et al.
patent: 3366679 (1968-01-01), Reinhold et al.
patent: 3505385 (1970-04-01), Reinhold et al.
Fieser, L. F. et al., Organic Chemistry, 3rd Edtn., (1956), Pub. Reinhold Pub. Corp., New York, p. 274 relied on.
Greenstein, J. P. et al., Chemistry of the Amino Acids, 1961-vol. 3, Pub. J. Wiley & Sons, N.Y., pp. 2174 & 2175 relied on.

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