Process for the preparation of ketoalkynoic acids and use of the

Details Process for the preparation of ketoalkynoic acids and use of the Process for the preparation of ketoalkynoic acids and use of the

1976-02-23

1977-05-31

McCarthy, Helen M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603409, 260415, 260468D, C11C 100, C07C 6900

Patent

active

040269116

ABSTRACT:
Reaction of a 2-methyl-2-(alkenyl)-1,3-dioxolane with an .alpha.,.omega.-dihalogenoalkane to obtain a 2-methyl-2-(.omega.-chloroalkynyl)-dioxolane, conversion of the latter to a corresponding nitrile, and hydrolysis of the nitrile to form a ketoalkynoic acid is a novel process for preparing the acid.
Use of the process in the synthesis of 2-(substituted)-cyclopentane-1,3,4-triones improves that synthesis.

REFERENCES:
patent: 3033884 (1962-05-01), Osbond et al.
patent: 3824262 (1974-07-01), Heslinga
Heather; J. B. et al., "Total Synthesis of Prostaglandins V. A Synthesis of (-)-Prostaglandine.sub.2 Via A Totally Asymmetric Process", Tetrahedron Letts. 25, pp. 2313-2316, (1973).
Sandler; S. R. et al., "Organic Functional Group Preparations", Academic Press, N.Y. (1968), pp. 68-69.
Morrison, R. T., et al., "Organic Chemistry", (third ed.), (1973), Allyn & Bacon, Boston, pp. 452 and 585-587.

Affiliated with

Also associated with

Rating

Process for the preparation of ketoalkynoic acids and use of the does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of ketoalkynoic acids and use of the, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of ketoalkynoic acids and use of the will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-657479