Process for the preparation of isosorbide-5-mononitrate

Details Process for the preparation of isosorbide-5-mononitrate Process for the preparation of isosorbide-5-mononitrate

1986-05-12

1987-12-15

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D49304

Patent

active

047134666

ABSTRACT:
A selective process for the preparation of isosorbide-5-mononitrate (I) ##STR1## from isosorbide-2,5-dinitrate (II) ##STR2## Said preparation is carried out by treating isosorbide-2,5-dinitrate with a suitable reduction system in the presence of not easily oxidizable coordinating metal ions.

REFERENCES:
patent: 4381400 (1983-04-01), Emeury et al.

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