Process for the preparation of isoflavones

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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07109358

ABSTRACT:
The invention relates to a process for the preparation of 2H-isoflavones which process comprises the reaction of a 2-hydroxyaryl alkyl ketone in the presence of a base with a formic-sulfuric anhydride salt which reaction is followed by neutralization. The procedure is especially suitable for the preparation of genistein.

REFERENCES:
V.G. Pivovarenko, et al., “Acetoformic Anhydride in the Synthesis of Chromones. 1. Synthesis of 3-Hetarylchromones”,Chem. Heterocycl. Compd.vol. 27, No. 5, pp. 496-501 (1991).
V.G. Pivovarenko, et al., “Mixed Anhydride of Acetic and Formic Acids in the Synthesis of Chromones. 2. Synthesis of 3-Arylchromones”,Chem. Heterocycl. Compd.vol. 28, No. 5, pp. 497-502 (1992).
V.G. Pivovarenko, et al., “Effective Synthesis of 7-Hydroxyisoflavone O-Glucosides”,Chem. Nat. Compd.vol. 24, No. 4, pp. 432-438 (1988).

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