Process for the preparation of iohexol

Details Process for the preparation of iohexol Process for the preparation of iohexol

1997-04-21

1998-12-08

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

424 9452, C07C23305

Patent

active

058472126

ABSTRACT:
Provided is a novel process for the preparation of iohexol having reduced number of isolated intermediates and significantly reduces or eliminates the use of ion-exchange resins required to desalinate the final product.

REFERENCES:
patent: 4250113 (1981-02-01), Nordal et al.
patent: 4348377 (1982-09-01), Felder et al.
patent: 5191119 (1993-03-01), Sovak et al.
patent: 5527926 (1996-06-01), Ranganathan et al.
J. Haavaldsen et al., "X-Ray Contrast Agents" ACTA Pharm. Suec. 20, 219-232 (1983).

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