Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2002-07-02
2008-09-02
Shiao, Rei-tsang (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C560S184000, C560S231000
Reexamination Certificate
active
07420078
ABSTRACT:
The invention relates to synthesis methods for the preparation of statin derivatives, which methods proceed by way of a key intermediate of formula I wherein X is halogen, acyloxy, activated hydrocarbyloxy, activated hydrocarbylthio or N(CH3)OCH3, Rais a hydroxy-protecting group, and Rbis a carboxy-protecting group, and, as well as to the compound of formula I, to further intermediates and methods for their preparation by Friedel-Crafts acylation.
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Baisch Gabriele
Burkhardt Stephan
End Nicole
Öhrlein Reinhold
Studer Martin
Ciba Specialty Chemicals Corp.
Kosack Joseph R
Shiao Rei-tsang
Wood Mervin G.
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