Process for the preparation of indoline derivatives

Details Process for the preparation of indoline derivatives Process for the preparation of indoline derivatives

1976-01-30

1978-01-24

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260289H, 26032611R, 424250, C07D48704

Patent

active

040703576

ABSTRACT:
Novel indoline derivatives of the formula ##STR1## wherein R is H or CH.sub.3 O and the X each are Cl or Br or collectively are --N(CH.sub.2 C.sub.6 H.sub.5)-- or acid addition salts thereof are obtained by treating a 3-hydroxy-1,2,3,4-tetrahydroquinoline of the formula ##STR2## with an inorganic acid halide and, if appropriate, the reacting resulting dihalogen compound with benzylamine or converting a resulting acid addition salt by treatment with a base in the free base or converting a free base by treatment with an acid to an acid addition salt.

REFERENCES:
patent: 3317524 (1967-05-01), Freed
patent: 3853878 (1974-12-01), Jonas et al.

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