Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-10-09
2000-10-17
Prats, Francisco
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
5361231, 536128, 514 54, 4241951, 435 99, 435101, C08B 3700
Patent
active
061334405
ABSTRACT:
The present invention provides a rapid and efficient method for the preparation and isolation of biologically active polysaccharides from Aloe. The present invention includes the activated mixture of polysaccharides (referred to herein as "Immuno-10"), produced by the methods of the invention. The invention also includes the use of the polysaccharides as immunostimulating, immunomodulating and wound healing agents. The resulting immunomodulatory complex has a higher activity and is more stable than bulk carbohydrates isolated using prior art alcohol precipitation schemes.
REFERENCES:
patent: 3470109 (1969-09-01), Marsh
patent: 3892853 (1975-07-01), Cobble
patent: 4178372 (1979-12-01), Coats
patent: 4555987 (1985-12-01), Tumlinson
patent: 4735935 (1988-04-01), McAnalley
patent: 4851224 (1989-07-01), McAnalley
patent: 4917890 (1990-04-01), McAnalley
patent: 4957907 (1990-09-01), McAnalley
patent: 4959214 (1990-09-01), McAnalley
patent: 4966892 (1990-10-01), McAnalley
patent: 5106616 (1992-04-01), McAnalley et al.
patent: 5118673 (1992-06-01), Carpenter et al.
patent: 5284833 (1994-02-01), McAnalley et al.
patent: 5308838 (1994-05-01), McAnalley et al.
patent: 5441943 (1995-08-01), McAnalley et al.
patent: 5443830 (1995-08-01), Moore et al.
patent: 5468737 (1995-11-01), McAnalley et al.
patent: 5512488 (1996-04-01), Eberendu et al.
patent: 5562906 (1996-10-01), Terry et al.
patent: 5587364 (1996-12-01), McAnalley et al.
patent: 5703060 (1997-12-01), McAnalley et al.
patent: 5773425 (1998-06-01), McAnalley et al.
patent: 5780453 (1998-07-01), McAnalley et al.
patent: 5786342 (1998-07-01), Carpenter et al.
patent: 5824659 (1998-10-01), Strickland et al.
Boericke (1985) Materia media with Respiratory, 9.sup.th Ed., B. Jain Pub. Pvt. Ltd., New Delhi, 679.
Brown (1995) The Herb Society of America; Encyclopedia of Herbs and Their Uses, Dorling Kinderstey Publ. Inc., 372.
Byeon et al. (1998) J. Investigative Dermatology 110:811-817.
Chevallier (1996) The Encyclopedia of Medicinal Plants, Dorling Kinderstey Pub. Inc., 151.
Gowda et al. (1979) Carbohydrate Research 72:201-205.
Gowda (1980) Carbohydrate Research 83:402-405.
Grieve (1971) A Modern Herbal, Dover Publication, Inc., New York, 70-71.
Hranisavljevic-Jakovljevic and Miljkovic-Stojanovic (1981) Bulletin de la Societe Chimique Beograd 46:269-273.
Krochmal (1973) A Guide to the Medicinal Plants of the United States, Quadrangle/The New York Times Book Co., New York, 238-239.
Lewis and Elvin-Lewis (1977) Medical Botany, John Wiley & Sons Pub. pp. 191, 243, 255, 289, 363.
Mandal and Das (1980) Carbohydrate Research 86:247-257.
Mandal and Das (1980) Carbohydrate Research 87:249-256.
Mandal et al. (1983) Indian J. Chemistry 22B:890-893.
Merck Index 9.sup.th Edition (1976) (Xanthoxylum p. 1299) (Berberine pp. 152-153) (Fagarine p. 515).
Paulsen et al. (1978) Carbohydrate Research 60:345-351.
Radjabi et al. (1983) Carbohydrate Research 116:166-170.
Radjabi-Nessab et al. (1984) Biochimie 66:563-567.
Wozniewski et al. (1990) Carbohydrate Research 198:387-391.
Yagi et al. (1984) J. Pharmaceutical Sciences 73:62-65.
Yagi et al. (1977) Planta Medica 31:17-20.
Danhof and McAnalley (Aug. 1983) Drug & Cosmetic Ind., pp. 52, 54, 105-106.
Day et al. (1922) J. Am. Pharm. Assoc. XI:462-463.
Fujita et al. (1976) Biochemical Pharmacology 25:205.
Haq and Hannan (1981) Bangladesh J. Sci. Ind. Res. XVI:68-72.
Ovodova et al. (1975) Chemical Abstracts 83:313, Ref. No. 93833a.
Robson et al. (1982) J. Burn Care Rehab. 3:157-163.
Shcherbukhin et al. (1979) A.N. Bakh Institute of Biochemistry, Academy of Sciences of the USSR, Moscow p. 666. Translated from Applied Biochemistry & Microbiology 15:892-896.
Shimizu et al. (1997) Chemical Abstracts 126:328, reference No. 126:197428v.
Smothers (Jan. 1983) Drug & Cosmetic Ind., pp. 40, 77-80.
Vilkas and Radjabi-Nassab (1986) Biochimie 68:1123-1127.
Waller et al. (1978) Proc. Okla. Acad. Sci. 58:69-76.
Waller et al. (1994) Cosmetics and Toiletries Manufacturing Worldwide 64-80.
Winters et al. (1981) Economic Botany 35:89-95.
Yagi et al. (1985) Experientia 41:669-671.
Mahiou Belaid
Qiu Zhihua
Prats Francisco
Univera Pharmaceuticals, Inc.
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