Process for the preparation of ifosfamide having improved proper

Details Process for the preparation of ifosfamide having improved proper Process for the preparation of ifosfamide having improved proper

1988-03-03

1989-11-21

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

C07F 924

Patent

active

048824526

ABSTRACT:
Ifosfamide having improved properties is obtained by crystallization from a solvent mixture selected from the group consisting of (a) a mixture of diethyl ether and a C.sub.1 -C.sub.3 alkanol or (b) a mixture of diisopropyl ether and a C.sub.1 -C.sub.3 alkanol under specific controlled conditions.

REFERENCES:
patent: 3732340 (1973-05-01), Arnold et al.
Carson et al., "Lab. Text, in Organic Chemistry", (1952), p. 19.

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