Process for the preparation of high-purity deferoxamine salts

Details Process for the preparation of high-purity deferoxamine salts Process for the preparation of high-purity deferoxamine salts

1993-05-27

1994-12-20

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfonic acids or salts thereof

562623, C07C30332

Patent

active

053747712

ABSTRACT:
A process for the preparation of high-purity deferoxamine salts from filtered fermentation liquors containing deferoxamine B as active ingredient by the adsorption of the active ingredient onto an ion exchange resin and the subsequent dissolution and purification thereof, which comprises carrying out the separation of the deferoxamine salt subsequent to the concentration of the eluate by salting out from an aqueous solution or from a mixture of water and an organic solvent and purifying it by repeated salting out and/or by methods known per se, and optionally

REFERENCES:
patent: 3471476 (1969-10-01), Goeumann et al.
patent: 3852424 (1974-12-01), Gaeumann et al.
patent: 4419365 (1983-12-01), McLachlan
patent: 4704274 (1987-11-01), Sakuma et al.
patent: 5235037 (1993-08-01), Krishnan
CA84(13): 87982c (1971.

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