Process for the preparation of heparin

Details Process for the preparation of heparin Process for the preparation of heparin

1979-07-02

1981-08-11

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C08B 3710

Patent

active

042835305

ABSTRACT:
Heparin is extracted from intestinal brine, i.e., from the brine which results from the preservation and dewatering treatment of animal tissue with sodium chloride, using conventional methods. The extracted product has a high activity and can subsequently be further purified to yield very high heparin activities.

REFERENCES:
patent: 2623001 (1952-12-01), Sylven
patent: 3058884 (1962-10-01), Mozen et al.
patent: 4119774 (1978-10-01), Andersson et al.
Physicians' Desk Reference, Publisher Charles E. Baker, Jr., Medical Economics Co., New Jersey, p. 545, 1980.
Lindahl, U., Biochem. Biophys. Acta., vol. 130, pp. 368-382 (1966).
Kiss, J., Survey article, "Chemical Structure of Heparin", circa, about 1976.
Ehrlich et al., J. Pharm. Sci., vol. 62, p. 517, 1973.

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