Process for the preparation of halogenated phenylmaloates

Details Process for the preparation of halogenated phenylmaloates Process for the preparation of halogenated phenylmaloates

1999-09-24

2000-12-05

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 6976

Patent

active

061569259

ABSTRACT:
A process for the preparation of dialkyl phenylmalonates of formula I, ##STR1## wherein R, R.sup.1, L.sup.1 and L.sup.2 have the meaning given in the claims which comprises treating an phenylbromide of formula II ##STR2## with a dialkyl malonate of formula III ##STR3## in an inert solvent in the presence of a base and a copper salt, wherein 1.0 mole of the phenylbromide of formula II is treated with the enolate obtained from 2.0 to 4.0 moles of the dialkyl malonate of formula III and 2.0 to 3.8 moles of the base.

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G.C. Finger et al., J. Am. Chem. Soc. 73, 153-155, 1951.

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