Process for the preparation of halogenated .beta.-lactam compoun

Details Process for the preparation of halogenated .beta.-lactam compoun Process for the preparation of halogenated .beta.-lactam compoun

1993-05-10

1996-07-02

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540222, C07D50102

Patent

active

055323537

ABSTRACT:
There is described the preparation of halogenated .beta.-lactam derivatives by introduction of a chlorine atom in the 3-position of the cephem nucleus starting from a 3-sulfonyloxycephem. Such starting materials are reacted with a chlorine ions donor in a basic medium.

REFERENCES:
patent: 4064343 (1977-12-01), Chauvette
patent: 5043439 (1991-08-01), Kant et al.
Chemical Abstracts, vol. 111.194375e, No. 21, 20 Nov. 1989, Columbus, Ohio, US.
The Journal Or Organic Chemistry, vol. 54, No. 20, 29 Sep. 1989, Washington, pp. 4962-4966 Vittorio Farina et al.
PCT Publication (WO 93/11132) (Nov. 27, 1992).

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