Process for the preparation of halogen-substituted 2-aminobenzot

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D27782

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045635331

ABSTRACT:
A process for the preparation of halogen-substituted 2-aminobenzothiazoles of the formula (1) ##STR1## starting from halogen-substituted phenylthioureas of the formula (2) ##STR2## by cyclization reaction with sulfuryl chloride in an inert solvent, wherein X is chlorine and/or bromine and n is an integer of from 1 to 4, and the cyclization reaction is carried out in the presence of an alkali metal or alkaline earth metal oxide, hydroxide or carbonate.

REFERENCES:
patent: 1910489 (1933-05-01), Lubs

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