Process for the preparation of glycoloylanilides

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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558415, 558416, 560 45, 562452, 562455, 564 86, 564142, 564156, 564200, 564201, 564395, 564396, 564397, 564398, C07C23333, C07C23102

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056167997

ABSTRACT:
A process for the preparation of glycoloylanilide of the formula (G) ##STR1## is recited that involves reacting a nitrobenzene with hydrogen and, if desired, with a carbonyl compound, in the presence of a noble metal catalyst and a solvent, reacting the compound produced with chloroacetyl chloride, reacting the resulting product with a benzyl alcohol and with a base, or reacting the resulting compound with an O-benzylglycoloyl chloride, and debenzylating the resulting benzylglycoloylanilide product by reacting with hydrogen in the presence of a noble metal catalyst. The invention also relates to a process for the preparation of O-benzylglycoloylanilide.

REFERENCES:
patent: 4334073 (1992-06-01), Diehr
patent: 5177261 (1993-01-01), McCarthy et al.

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