Process for the preparation of glycidyl derivatives

Details Process for the preparation of glycidyl derivatives Process for the preparation of glycidyl derivatives

2004-08-19

2008-12-02

Dentz, B. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S514000

Reexamination Certificate

active

07459572

ABSTRACT:
There is provided a process for preparing a glycidyl derivative from 3-chloro-1,2-propanediol, comprising i) adding a phosphate salt to a solution into which 3-chloro-1,2-propanediol is dissolved into a solvent to produce glycidol, and ii) adding to the solution of step i) a base capable of releasing a glycidyl group from the glycidol and a substrate susceptible to nucleophilic attack to produce the desired glycidyl derivative by nucleophilic attack of the glycidyl group to the substrate.

REFERENCES:
patent: 4946974 (1990-08-01), Sharpless et al.
patent: 5965753 (1999-10-01), Masaki et al.
patent: 0 884 313 (1998-12-01), None

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