Process for the preparation of functional fluoro derivatives

Details Process for the preparation of functional fluoro derivatives Process for the preparation of functional fluoro derivatives

1989-04-27

1991-01-08

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568364, 568437, 568495, C07C 4500, C07C 4543

Patent

active

049837761

ABSTRACT:
The invention relates to the synthesis of functional fluoro derivatives and more particularly that of perfluorinated aldehydes of the type R.sub.F -CHO where R.sub.F denotes a linear or branched perfluoroalkyl radical.
A perfluoroalkyl iodide R.sub.F I is reacted over the zinc-copper metal couple, in the presence of a radical initiator, with an amide RCONR.sub.1 R.sub.2, R denoting a hydrogen atom or a methyl or ethyl radical, and each of R.sub.1 and R.sub.2 denoting a C.sub.1 -C.sub.4 alkyl radical.

REFERENCES:
patent: 2568500 (1951-09-01), Husted et al.
patent: 2574832 (1951-11-01), Kharasch
patent: 4484993 (1984-11-01), Ishikawa et al.
patent: 4760195 (1988-07-01), Kubo et al.
patent: 4837366 (1989-06-01), Murata et al.
E. T. McBee, et al., Reactions of Perfluoronitriles With Grignard Reagents, pp. 917-919, Feb. 20, 1955.
Yu. V. Zeifman, et al., Combined Addition of Fluorocarbanions and Electrophilic Reagents to Fluoroolefins, pp. 212-215, Plenum Publishing Corporation (1983).
Yanchang Shen, et al., A Convenient Synthesis of Terminal Perfluoroacylacetylenes and Perfluoroalkynals, pp. 159-160, Communications (Feb. 1985).
Coe, et al., Aromatic Polyfluoro-Compounds, Part XI, Pentafluorophenyl-lithium and Derived Compounds, pp. 3227-3231, 622, J. Amer. Chem. Soc. (1962).
Vorozhtsov, Jr., et al., Preparation and Reactions of Pentafluorophenyl and Pentafluoronaphthylmagnesium Chlorides, Institute of Organic Chemistry, pp. 1135-1139, vol. 159, (1964).
Organometallic Compounds, p. 4046, vol. 62 (1965).

Affiliated with

Also associated with

Rating

Process for the preparation of functional fluoro derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of functional fluoro derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of functional fluoro derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-936125