Process for the preparation of ferutinine from Ferula...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

Reexamination Certificate

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C424S074000

Reexamination Certificate

active

07371886

ABSTRACT:
The invention relates to a process for the preparation of ferutinine (Ia) fromFerulaspp extracts comprising basic hydrolysis of the extracts and treatment with p-pivaloyloxybenzoic acid. The invention relates also to the use of the extracts and ferutinine in the cosmetic and dermatological field

REFERENCES:
patent: 672 251 (1989-11-01), None
patent: 1 604 225 (1981-12-01), None
K.Tamemoto, Y.Takaishi, B.Chen, K.Kawazoe, H.Shibata, T.Higuti, G.Honda, M.Ito, Y.Takeda, O.K.Kodzhimatov, O.Ashurmetov. Sequiterpenoids from the fruits ofFerula kuhistanicaand antibacterial activity of the constituents ofF. kuhistanica.Phytochemistry, 763-767, 58, 2001.
G.A. Tolstikov, F.A. Akbutina, A.D. Dembitskii, F.A. Valeev, and M.S. Miftakhov. Prostanoids LVIII—New a,w-Noranalogs of prostaglandins from ferutinolZhurnal Organicheskoi Khimii (or J. Org. Chem. USSR trasnlated), vol. 28, No. 10, pp. 2081-2090, Oct. 1992.
Tamemoto Kimiko et al: “Sesquiterpenoids from the fruits ofFerula kuhistanicaand antibacterial activity of the constituents ofF. kuhistanica” Phytochemistry (Oxford), vol. 58, No. 5, Nov. 2001, pp. 763-767, XP004310053 ISSN: 0031-9422 p. 765, paragraph 5; table 3; compound 4.
Galal A M et al: “Daucane sesquiterpenes fromFerula hermonis.” Journal of Natural Products. Mar. 2001, vol. 64, No. 3, Mar. 2001; pp. 399-400, XP002290428 ISSN: 0163-3864 abstract; compound 3.
Patent Abstracts of Japan vol. 2000, No. 24, May 11, 2001 & JP 2001 206819 A (Shansho Seiyaku Co Ltd), Jul. 31, 2001 abstract.

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