Process for the preparation of ethynylcyclopropane

Details Process for the preparation of ethynylcyclopropane Process for the preparation of ethynylcyclopropane

1998-12-04

1999-12-14

Griffin, Walter D.

Chemistry of hydrocarbon compounds

Unsaturated compound synthesis

Triple-bond product

585357, 585638, 585639, 585640, 585 20, C07C 200

Patent

active

060020628

ABSTRACT:
Ethynylcyclopropane is prepared from (1,1-dimethoxyethyl)cyclopropane by a two-stage elimination of methanol. Ethynylcyclopropane is an intermediate in the synthesis of pharmaceutically active ingredients, for example, antiviral agents.

REFERENCES:
patent: 4395580 (1983-07-01), Juguin et al.
"Fine Chemistry with Small Rings-Cyclopropyl Compounds for Efficient Synthesis", New Aspects Org.Chem II, Proc. Int. Kyoto Conf. 5th (60 UNAD); pp. 181-213, 1992 No Month.
Taskinen, E., Acta Chemica Scandinavica. Series B.--Organic Chemistry and Biochemistry, vol. 28, No. 3, (1974), pp. 357 to 366, (Taskinen) -No Month .

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