Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1997-08-28
1998-09-01
Geist, Gary
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544249, C07D23900
Patent
active
058012451
ABSTRACT:
The known blood platelet reducing agent Anagrelide is prepared via an improved process starting with commercially available 2,3-dichlorotoluene and involving novel intermediates represented by the formulas: ##STR1## wherein Y is Br, Cl or I. Compound (G) is reacted with ethyl glycine to form the well-known intermediate ethyl-N-(2,3-dichloro-6-nitro benzyl) glycine which is then used following conventional process steps to form Anagrelide.
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Geist Gary
Roberts Laboratories Inc.
Vollano Jean F.
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