Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound
Patent
1995-02-15
1997-01-14
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing nitrogen-containing organic compound
435119, 435120, 435121, 435122, 435280, C12P 1302, C12P 1718, C12P 1714, C12P 1710
Patent
active
055938710
ABSTRACT:
This invention relates to the enantioselective biologically-catalyzed hydrolysis of certain racemic nitriles to the corresponding R- or S-amides, chemically or biologically-catalyzed hydrolysis of the amides to the corresponding R- or S-acids in a batch process or in a continuous process that employs racemization and recycling of enantiomeric nitrile intermediates, the racemic nitriles being selected from the group, A--C(R.sup.1)(R.sup.2)CN, wherein A, R.sup.1 and R.sup.2 are as defined in the text, as well as certain biological materials employed to catalyze the process.
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Anton David L.
Fallon Robert D.
Stieglitz Barry
Witterholt Vincent G.
E. I. Du Pont de Nemours and Company
Marx Irene
Saucier S.
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