Process for the preparation of echinocandin derivatives

Details Process for the preparation of echinocandin derivatives Process for the preparation of echinocandin derivatives

2006-12-12

2006-12-12

Tsang, Cecilia J. (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

C514S002600, C514S009100, C514S011400, C530S300000, C530S317000

Reexamination Certificate

active

07148322

ABSTRACT:
A subject of the invention is a process for the preparation of the compounds of formula (I):R being as defined in the description as well as their salts, the intermediates, the use of the dihydrochloride as a medicament and the pharmaceutical compositions containing them. The process for preparing formula (I) leads to greater than 50% yields of isomer A, and its intended use, e.g. as an antifungal medicament.

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