Process for the preparation of donepezil

Details Process for the preparation of donepezil Process for the preparation of donepezil

2005-01-18

2005-01-18

Tsang, Cecilia J. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S195000, C546S233000

Reexamination Certificate

active

06844440

ABSTRACT:
The invention provides a process for the preparation of a compound of the formula 6 comprising the hydrolysis and decarboxylation of a compound of the formula 5 according to the reaction:wherein R and R2independently a C1-C4alkyl group or an aralkyl group.

REFERENCES:
patent: 5606064 (1997-02-01), Lensky
patent: 6252081 (2001-06-01), Iimura
patent: 296560 (1996-02-01), None
patent: 711756 (1998-07-01), None
patent: WO 9722584 (1997-06-01), None
patent: WO 9936405 (1999-07-01), None

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