Process for the preparation of dispersible colloidal systems of

Details Process for the preparation of dispersible colloidal systems of Process for the preparation of dispersible colloidal systems of

1991-03-06

1992-12-29

Stoll, Robert L.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

264 41, 424450, 4284022, A61K 9127, B01J 1312

Patent

active

051749300

ABSTRACT:
Dispersible colloidal systems of amphiphilic lipids in the form of oligolamellar liposomes of submicron dimensions are prepared by combining a first liquid phase consisting essentially of a solution of the lipids with a greater amount of a second liquid phase consisting essentially of water. The solvent for the first liquid phase is miscible in all proportions with water. If desired, the first liquid phase may also contain a substance A in solution therewith, such as cholesterol. An additional substance B, which is a biologically active substance, may be present in the first phase if it is lipophilic, and in the second phase if it is hydrophilic.

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