Process for the preparation of difluorobenzamide

Details Process for the preparation of difluorobenzamide Process for the preparation of difluorobenzamide

1990-08-21

1993-04-27

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

4352532, 4352521, 435872, C12P 1302, C12N 120

Patent

active

052061582

ABSTRACT:
The invention provides a process for the preparation of 2,6-difluorobenzamide which comprises subjecting 2,6-difluorobenzonitrile to the action of a suitable hydrolysing microorganism or nitrilase extract therefrom; and Rhodococcus Sp. NCIB 12218 or a mutant thereof, suitable for use in the process.

REFERENCES:
patent: 4629700 (1986-12-01), Prevatt
Goodfellow et al., The Biology of the Actinomycetes, Academic Press, 1984, pp. 91-94.
Harper, D, Biochem J. vol. 165, pp. 309-319, 1977.

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